In addition to the discovery that the rate of release of corticosterone is essential for hormonal response to stress and good behavior Sarabdjitsingh discovered that the protein suffers mainly from a broken rhythm: the glucocorticoid receptor. This protein could be an ideal target for the treatment of stress and stress-related illnesses.Every hour the adrenal glands to release cortisol, a stress hormone (corticosterone in rats). However, disease or aging can cause considerable discomfort to rate this program with the result that the body responds less well to stress and pressure. Sarabdjitsingh studied how the rate affects the stress response and resilience of the hormonal stress response and behavior. He also studied whether changes in the model took place in the tissues affected by the stress hormone.

Angela Sarabdjitsingh achieved this to be the first to combine a series of advanced techniques. Sarabdjitsingh only conducted his research with a grant from the NWO Mosaic program. Mosaic is a grant program that funds research for PhD students from ethnic minorities. Ethnic minorities are underrepresented in science and the New World Order, as a strong supporter of diversity, regrets the small number of role models. With Mosaic, NWO wants to prevent scientific talent to be needlessly lost.

Source: NWO (Netherlands Organisation for Scientific Research), AlphaGalileo Foundation.